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- 规格参数
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Biochem/physiol Actions
BAY-678 is an orally available, highly potent and selective inhibitor of human neutrophil elastase (HNE). For full characterization details, please visit the BAY-678 probe summary on the Structural Genomics Consortium (SGC) website.
BAY-677 is used as a negative control and is available from Sigma. To learn more about and purchase BAY-677, click here.
To learn about other SGC chemical probes for protein targets, visit sigma.com/sgc
BAY-678 is an orally available, highly potent and selective inhibitor of human neutrophil elastase.
Features and Benefits
BAY-678 is a chemical probe available through a partnership with the Structural Genomics Consortium (SGC). To learn more and view other SGC chemical probes, visit sigma.com/SGC.
| Quality Segment | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| optical activity | [α]/D +21 to +29°, c = 0.5 in methanol |
| color | white to light brown |
| solubility | DMSO: 20 mg/mL, clear |
| storage temp. | 2-8°C |
| SMILES string | CC(N1C2=CC=CC(C(F)(F)F)=C2)=C(C(C)=O)[C@@H](C3=CN=C(C#N)C=C3)NC1=O |
| InChI | 1S/C20H15F3N4O2/c1-11-17(12(2)28)18(13-6-7-15(9-24)25-10-13)26-19(29)27(11)16-5-3-4-14(8-16)20(21,22)23/h3-8,10,18H,1-2H3,(H,26,29)/t18-/m1/s1 |
| InChI key | PGIVGIFOWOVINL-GOSISDBHSA-N |
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