- 商品介绍
- 规格参数
- 包装参数
产品介绍
Product Description
Biochem/physiol Actions
GSK923295 is an allosteric inhibitor of CENP-E kinesin motor ATPase activity. It inhibits release of inorganic phosphate and stabilizes CENP-E motor domain interaction with microtubules, which causes failure of metaphase chromosome alignment and induces mitotic arrest. GSK923295 induces tumor cell apoptosis and tumor regression
Selective and potent allosteric inhibitor of CENP-E kinesin motor ATPase activity
技术参数
Specifications
| Quality Segment | 100 |
| assay | ≥95% (HPLC) |
| form | powder |
| color | white to beige |
| solubility | DMSO: 2 mg/mL, clear |
| storage temp. | -10 to -25°C |
| SMILES string | Clc1c(ccc(c1)C(=O)N[C@H](CNC(=O)CN(C)C)Cc2ccc(cc2)c3nc4[n](c3)C=CC=C4[C@@H](O)C)OC(C)C |
| InChI key | WHMXDBPHBVLYRC-OFVILXPXSA-N |
| 长度(mm) | |
| 宽度(mm) | |
| 高度(mm) | |
| 重量(kg) |
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