Anti-GLUD1 antibody produced in rabbit,100UL,SAB5701596-100UL,Sigma

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订货号 0BP5058
品牌型号 Sigma SAB5701596-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

This gene encodes glutamate dehydrogenase, which is a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. This enzyme has an important role in regulating amino acid-induced insulin secretion. It is allosterically activated by ADP and inhibited by GTP and ATP. Activating mutations in this gene are a common cause of congenital hyperinsulinism. Alternative splicing of this gene results in multiple transcript variants. The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of glutamate dehydrogenase. Related pseudogenes have been identified on chromosomes 10, 18 and X. [provided by RefSeq, Jan 2016]


Immunogen

A synthesized peptide derived from human GLUD1


Physical form

Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.


技术参数 Specifications
biological sourcerabbit
Quality Segment100
conjugateunconjugated
antibody product typeprimary antibodies
clonemonoclonal
formliquid
species reactivitymouse, rat, human
concentration0.51 mg/mL
technique(s)immunohistochemistry: 1:50-1:200,western blot: 1:500-1:2000
UniProt accession no.P00367
shipped inwet ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... GLUD1(2746)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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