Monoclonal Anti-GRIN2B antibody produced in mouse,100UG,SAB1402214-100UG,Sigma

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订货号 0BP4483
品牌型号 Sigma SAB1402214-100UG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA receptor channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of three different subunits: NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The NR2 subunit acts as the agonist binding site for glutamate. This receptor is the predominant excitatory neurotransmitter receptor in the mammalian brain. (provided by RefSeq)


Immunogen

GRIN2B (NP_000825, 127 a.a. ~ 236 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
HGGSSMIMADKDESSMFFQFGPSIEQQASVMLNIMEEYDWYIFSIVTTYFPGYQDFVNKIRSTIENSFVGWELEEVLLLDMSLDDGDSKIQNQLKKLQSPIILLYCTKEE


Physical form

Solution in phosphate buffered saline, pH 7.4


技术参数 Specifications
biological sourcemouse
Quality Segment100
conjugateunconjugated
antibody formpurified immunoglobulin
antibody product typeprimary antibodies
clone2G5, monoclonal
formbuffered aqueous solution
mol wtantigen ~38.21 kDa
species reactivityhuman
technique(s)capture ELISA: suitable,indirect ELISA: suitable,proximity ligation assay: suitable,western blot: 1-5 μg/mL
isotypeIgG2aκ
NCBI accession no.NM_000834
UniProt accession no.Q13224
shipped indry ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... GRIN2B(2904)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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