Monoclonal Anti-UCP1 antibody produced in mouse,100UG,WH0007350M1-100UG,Sigma

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订货号 0BP2650
品牌型号 Sigma WH0007350M1-100UG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

Mitochondrial uncoupling proteins (UCP) are members of the family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed only in brown adipose tissue, a specialized tissue which functions to produce heat. (provided by RefSeq)


Immunogen

UCP1 (NP_068605, 232 a.a. ~ 267 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
PVDVVKTRFINSPPGQYKSVPNCAMKVFTNEGPTAF


Physical form

Solution in phosphate buffered saline, pH 7.4


Legal Information

GenBank is a registered trademark of United States Department of Health and Human Services


Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


技术参数 Specifications
biological sourcemouse
Quality Level100
conjugateunconjugated
antibody formpurified immunoglobulin
antibody product typeprimary antibodies
clone4E5, monoclonal
formbuffered aqueous solution
species reactivityhuman
technique(s)indirect ELISA: suitable,western blot: 1-5 μg/mL
isotypeIgG2aκ
GenBank accession no.NM_021833
UniProt accession no.P25874
shipped indry ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... UCP1(7350)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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