Monoclonal Anti-MUC1 antibody produced in mouse,100UG,SAB1404092-100UG,Sigma

销售价: ¥ 4546.19 / 件
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订货号 0BP2255
品牌型号 Sigma SAB1404092-100UG
货期 询货期
最小订货量 1件
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  • 商品介绍
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产品介绍 Product Description

General description

This gene is a member of the mucin family and encodes a membrane bound, glycosylated phosphoprotein. The protein is anchored to the apical surface of many epithelia by a transmembrane domain, with the degree of glycosylation varying with cell type. It also includes a 20 aa variable number tandem repeat (VNTR) domain, with the number of repeats varying from 20 to 120 in different individuals. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length nature of only some has been determined. (provided by RefSeq)


Immunogen

MUC1 (NP_877418.1, 315 a.a. ~ 420 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
NSSLEDPSTDYYQELQRDISEMFLQIYKQGGFLGLSNIKFRPGSVVVQLTLAFREGTINVHDMETQFNQYKTEAASRYNLTISDVSVSDVPFPFSAQSGAGVPGWG


Physical form

Solution in phosphate buffered saline, pH 7.4


Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


技术参数 Specifications
biological sourcemouse
Quality Level100
conjugateunconjugated
antibody formpurified immunoglobulin
antibody product typeprimary antibodies
clone1B7, monoclonal
formbuffered aqueous solution
mol wtantigen ~37.77 kDa
species reactivityhuman
technique(s)capture ELISA: suitable,indirect ELISA: suitable,western blot: 1-5 μg/mL
isotypeIgG2aκ
NCBI accession no.NM_182741
UniProt accession no.P15941
shipped indry ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... MUC1(4582)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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