Anti-PLC gamma 1 (PLCG1) Antibody, clone 6V9U10, Rabbit Monoclonal,100UL,SAB5702631-100UL,Sigma

销售价: ¥ 3636.13 / 件
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订货号 0BP1944
品牌型号 Sigma SAB5702631-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]


Immunogen

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Recombinant fusion protein containing a sequence corresponding to amino acids 710-832 of human PLC gamma 1 (PLC gamma 1 (PLCG1)) (P19174).


Application

WB


技术参数 Specifications
biological sourcerabbit
Quality Level100
conjugateunconjugated
materialcolorless
clone6V9U10, monoclonal
formliquid
mol wt 150 kDa
species reactivityhuman, rat
concentration0.44 mg/mL
technique(s)western blot: 1:500 - 1:2000
color colorless
isotypeIgG
immunogen sequenceGKIKHCRVQQEGQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEEALEKIGTAEPDYGALYEGRNPGFYVEANPMPTFKCAVKALFDYKAQREDELTFIKSAIIQNVEKQEGGWWRGD
UniProt accession no.P19174
shipped inwet ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... PLCG1(5335)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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