- 商品介绍
- 规格参数
- 包装参数
General description
The Human Shh-N (Sonic Hedgehog N Terminus) ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme- linked immunosorbent assay for the quantitative measurement of human Shh-N in serum, plasma, cell culture supernatants and urine.
Immunogen
Recombinant Human ShhN
Application
请参考Protocol了解详情。
Biochem/physiol Actions
Sonic hedgehog (Shh) is a secreted glycoprotein involved in embryonic morphogenic development of several tissues. It has a role in fracture healing and regeneration. In the canonical pathway, the protein associates with its receptor patched (Ptc-1), de-represses smoothened (Smo) and activates the Gli family of transcription factors. Mutations in the Shh pathway have been linked to developmental diseases and cancer. Shh plays a vital role in axon growth and guidance throughout the brain development. Shh stimulates neurite outgrowth by overcoming neurite growth inhibitory environment associated with glial scar.
Other Notes
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
| species reactivity | human |
| packaging | kit of 96 wells (12 strips x 8 wells) |
| technique(s) | ELISA: suitable,capture ELISA: suitable |
| input | sample type cell culture supernatant(s) sample type serum sample type urine sample type plasma |
| assay range | inter-assay cv: <12% intra-assay cv: <10% sensitivity: 42 pg/mL standard curve range: 40.96-10000 pg/mL (Assay Diluent C),inter-assay cv: <12% intra-assay cv: <10% sensitivity: 8 pg/mL standard curve range: 40.96-10000 pg/mL (Assay Diluent B) |
| detection method | colorimetric |
| shipped in | wet ice |
| storage temp. | −20°C |
| Gene Information | human ... SHH(6469) |
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