Anti-Phospho-ESRα-S118 antibody produced in rabbit,100UL,SAB5701845-100UL,Sigma

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订货号 0BP1634
品牌型号 Sigma SAB5701845-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined. [provided by RefSeq, Mar 2014]


Immunogen

A phospho specific peptide corresponding to residues surrounding S118 of human Estrogen Receptor alpha (ESR1)


Physical form

Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.


技术参数 Specifications
biological sourcerabbit
Quality Level100
antibody product typeprimary antibodies
clonemonoclonal
formliquid
species reactivityhuman
concentration1.5 mg/mL
technique(s)western blot: 1:500-1:2000
UniProt accession no.P03372
shipped inwet ice
storage temp.−20°C
target post-translational modificationphosphorylation (pSer118)
Gene Informationhuman ... ESR1(2099)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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