Anti-LXRα antibody produced in rabbit,100UL,SAB5701490-100UL,Sigma

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订货号 0BP1496
品牌型号 Sigma SAB5701490-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

The protein encoded by this gene belongs to the NR1 subfamily of the nuclear receptor superfamily. The NR1 family members are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. This protein is highly expressed in visceral organs, including liver, kidney and intestine. It forms a heterodimer with retinoid X receptor (RXR), and regulates expression of target genes containing retinoid response elements. Studies in mice lacking this gene suggest that it may play an important role in the regulation of cholesterol homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]


Immunogen

A synthesized peptide derived from human LXRα


Physical form

Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.


技术参数 Specifications
biological sourcerabbit
Quality Level100
conjugateunconjugated
antibody product typeprimary antibodies
clonemonoclonal
formliquid
species reactivitymouse, rat
concentration0.31 mg/mL
technique(s)immunohistochemistry: 1:50-1:200,western blot: 1:500-1:2000
UniProt accession no.Q13133
shipped inwet ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... NR1H3(10062)
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高度(mm)
重量(kg)
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