EPHB4 (561-end), active, GST tagged human,10UG,E7282-10UG,Sigma

销售价: ¥ 3888.73 / 件
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订货号 0BP0876
品牌型号 Sigma E7282-10UG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

EPHB4 (Ephb1 Eph receptor B4) belongs to EPHB receptor family, which is the biggest family of transmembrane tyrosine kinase receptors. Mammals contain five EPHB receptors, namely, EPHB1-EPHB4 and EPHB6. Their ligands are transmembrane in nature and are called ephrinB1, -B2 and -B3.


Biochem/physiol Actions

EPHB4 (ephrin receptor B4) is a member of the Eph family of receptor tyrosine kinases which play a role in regulating cell adhesion and cell movement during embryonic development. Furthermore, because tissue disorganization and abnormal cell adhesion, movement, and survival characterize the more advanced stages of cancer, the inappropriate functioning of Eph receptor could play a causal role in malignancy. Furthermore, EPHB4 has been shown to be the major essential interaction partner of Ephrin B2 in angiogenesis.


Physical form

Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.2 5mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.


Legal Information

PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany


技术参数 Specifications
recombinantexpressed in baculovirus infected Sf9 cells
Quality Level200
product linePRECISIO® Kinase
assay≥70% (SDS-PAGE)
formbuffered aqueous glycerol solution
specific activity349-472 nmol/min·mg
mol wt ~50 kDa
UniProt accession no.P54760
shipped indry ice
storage temp.−70°C
Gene Informationhuman ... EPHB4(2050)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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