- 商品介绍
- 规格参数
- 包装参数
General description
Chemical structure: aminoglycoside
Application
Gentamicin solution has been used to study its dose-related antipruritic effects on serotonin (5-HT)-induced scratching model. It has also been used in electrophysiological analysis.
Biochem/physiol Actions
作用机制:庆大霉素可通过与核糖体的30S亚基结合来抑制蛋白质合成。
抗菌谱:包括革兰氏阴性和革兰氏阳性细菌,包括对于四环素,氯霉素,卡那霉素和粘菌素,某些特定假单胞菌菌株,变形杆菌属,Staphylococcus 和Streptococcus的抗性。
Other Notes
Gentamicin is an aminoglycoside complex produced by fermentation of Micromonospora purpurea or M. echinospora. It is used as the sulfate salt. There are three components, each consisting of five basic nitrogens and requiresing five equivalents of sulfuric acid per mole of gentamicin base.
Legal Information
Hybri-Max is a trademark of Sigma-Aldrich Co. LLC
Disclaimer
The product is stable at 37° for 5 days and is stored at 2-8°C.
| grade | Hybri-Max™ |
| Quality Level | 300 |
| sterility | 0.1 μm filtered |
| product line | BioReagent |
| form | liquid |
| quality | Prepared in tissue culture grade water. |
| concentration | 50 mg/mL gentamicin |
| technique(s) | cell culture | hybridoma: suitable |
| impurities | endotoxin, tested |
| color | colorless to light yellow |
| density | 1.000 g/cm3 |
| web metadata keyword.default | aminoglycoside antibiotic, Gram-negative bacteria, bactericidal antibiotic, gentamycin, tissue culture use |
| antibiotic activity spectrum | Gram-negative bacteria,Gram-positive bacteria,mycoplasma |
| mode of action | protein synthesis | interferes |
| storage temp. | 2-8°C |
| SMILES string | OS(O)(=O)=O.CN[C@@H]1[C@@H](O)[C@H](OC[C@]1(C)O)O[C@H]2[C@H](N)C[C@H](N)[C@@H](O[C@H]3O[C@H](CN)CC[C@H]3N)[C@@H]2O.CN[C@@H]4[C@@H](O)[C@H](OC[C@]4(C)O)O[C@H]5[C@H](N)C[C@H](N)[C@@H](O[C@H]6O[C@@H](CC[C@H]6N)[C@@H](C)N)[C@@H]5O.CN[C@H](C)[C@@H]7CC[C@@H](N)[C@H](O7)O[C@@H]8[C@@H](N)C[C@@H](N)[C@H](O[C@H]9OC[C@](C)(O)[C@H](NC)[C@H]9O)[C@H]8O |
| InChI | 1S/C21H43N5O7.C20H41N5O7.C19H39N5O7.H2O4S/c1-9(25-3)13-6-5-10(22)19(31-13)32-16-11(23)7-12(24)17(14(16)27)33-20-15(28)18(26-4)21(2,29)8-30-20;1-8(21)12-5-4-9(22)18(30-12)31-15-10(23)6-11(24)16(13(15)26)32-19-14(27)17(25-3)20(2,28)7-29-19;1-19(27)7-28-18(13(26)16(19)24-2)31-15-11(23)5-10(22)14(12(15)25)30-17-9(21)4-3-8(6-20)29-17;1-5(2,3)4/h9-20,25-29H,5-8,22-24H2,1-4H3;8-19,25-28H,4-7,21-24H2,1-3H3;8-18,24-27H,3-7,20-23H2,1-2H3;(H2,1,2,3,4)/t9-,10-,11+,12-,13+,14+,15-,16-,17+,18-,19-,20-,21+;8-,9-,10+,11-,12+,13+,14-,15-,16+,17-,18-,19-,20+;8-,9+,10-,11+,12-,13+,14+,15-,16+,17+,18+,19-;/m110./s1 |
| InChI key | RDEIXVOBVLKYNT-HDZPSJEVSA-N |
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