- 商品介绍
- 规格参数
- 包装参数
General description
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the centromeric copy.
Immunogen
A synthetic acetylated peptide around K5 of human Histone H4 (NP_001029249.1).
Physical form
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Preparation Note
Store at -20℃. Avoid freeze / thaw cycles.
| biological source | rabbit |
| Quality Level | 100 |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| form | buffered aqueous solution |
| mol wt | 11 |
| species reactivity | human, mouse, rat |
| concentration | 1.28 mg/ml |
| technique(s) | ChIP: 1:20-1:100,immunofluorescence: 1:50-1:200,immunohistochemistry: 1:50-1:200,western blot: 1:200-1:2000 |
| UniProt accession no. | P62805 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | acetylation (Lys5) |
| Gene Information | human ... H4C14(8370) |
| 长度(mm) | |
| 宽度(mm) | |
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| 重量(kg) |
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