- 商品介绍
- 规格参数
- 包装参数
General description
This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human malignancies, including colon cancer and renal cell carcinoma. Alternative splicing results in multiple transcript variants.
Immunogen
Recombinant protein of human PD‐L1 extracellular domain.
Physical form
Tris Buffer, pH7.3-7.7, with 1% BSA and <0.1% Sodium azide.
| biological source | mouse |
| Quality Level | 100 |
| conjugate | unconjugated |
| antibody product type | primary antibodies |
| clone | monoclonal |
| form | liquid |
| species reactivity | rat, mouse, monkey, human |
| concentration | 1.51 mg/mL |
| technique(s) | immunohistochemistry: 1:50-1:200,western blot: 1:500-1:2000,immunohistochemistry: 1:50-1:100 |
| UniProt accession no. | Q9NZQ7 |
| shipped in | wet ice |
| storage temp. | 2-8°C |
| target post-translational modification | unmodified |
| Gene Information | human ... PD-L1(29126) |
| 长度(mm) | |
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| 重量(kg) |
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¥ 4039.86
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¥ 8293.41
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¥ 1724.25
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瓶顶过滤器-500ml容量,MF75TM系列，聚苯乙烯外壳，75mmPES滤膜，孔径0.45um,适合瓶颈尺寸33mm，12/箱，295-3345，Nalgene，Thermofisher，赛默飞世尔¥ 1938.54
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¥ 2173.94
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¥ 8072.66
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¥ 26022.64
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¥ 37675.92
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¥ 51018.02
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¥ 42661.77
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¥ 22137.02
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