- 商品介绍
- 规格参数
- 包装参数
Biochem/physiol Actions
SMBA1 is a potent and selective Bax agonist.
SMBA1 is an anti-tumor agent. It exhibits anti-proliferative effects against glioblastoma (GBM) cells.
Small-molecule Bax agonists 1 (SMBA1) is a potent and selective Bax agonist that binds to Bax, induces conformational change which blocks Bax S184 phosphorylation. SMBA1 induces apoptosis in cancer cells and suppresses lung tumor growth in vivo without significant normal tissue toxicity. SMBA1 does not bind to other B-cell lymphoma 2 (Bcl-2) family members.
| Quality Level | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| color | white to beige |
| solubility | DMSO: 20 mg/mL, clear |
| storage temp. | −20°C |
| SMILES string | OC(C=CC=C1)=C1/C=C2C(C=CC=C3)=C3C4=C\2C=C([N+]([O-])=O)C=C4 |
| InChI | 1S/C20H13NO3/c22-20-8-4-1-5-13(20)11-18-16-7-3-2-6-15(16)17-10-9-14(21(23)24)12-19(17)18/h1-12,22H/b18-11+ |
| InChI key | PEYKRJBXACUOOB-WOJGMQOQSA-N |
| 长度(mm) | |
| 宽度(mm) | |
| 高度(mm) | |
| 重量(kg) |
-
询价
-
询价
-
询价
-
¥ 2814.26
-
¥ 2019.57
-
¥ 4039.86
-
¥ 8293.41
-
询价
-
询价
-
询价
-
¥ 3152.47
-
¥ 238.17
-
询价
-
询价
-
¥ 5167.58
-
¥ 3290.05
-
询价
-
询价
-
¥ 5014.59
-
¥ 2888.88
微信小程序
7X24小时在线咨询