KD-Validated Anti Uracil DNA Glycosylase Antibody, clone 24GB2530, Rabbit Monoclonal，1004G，SAB6012457-100UL，Sigma 供应商、价格、厂家、报价、规格参数

产品介绍 Product Description

General description

This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. The UNG2 term was used as a previous symbol for the CCNO gene (GeneID 10309), which has been confused with this gene, in the literature and some databases. [provided by RefSeq, Nov 2010]
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Immunogen

A synthesized peptide corresponding to a sequence within amino acids 20-88 of human UNG [NP_550433.1].

Physical form

Solution in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.

Other Notes

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.

技术参数 Specifications

biological source	rabbit (Monoclonal)
Quality Level	100
recombinant	expressed in HEK 293 cells
conjugate	unconjugated
antibody form	affinity isolated antibody
antibody product type	primary antibodies
clone	24GB2530, recombinant monoclonal
form	buffered aqueous glycerol solution
mol wt	35 kDa
species reactivity	human
packaging	vial of 1.5 mL
enhanced validation	recombinant expression Learn more about Antibody Enhanced Validation
sustainability	Greener Alternative Product
concentration	0.705 mg/ml
technique(s)	flow cytometry: 1:2000,immunofluorescence: 1:100-:1000,western blot: 1:1,000-1:5,000
isotype	IgG
Ensembl \| human accession no.	ENSG00000076248
NCBI accession no.	NP_550433.1
UniProt accession no.	P13051
greener alternative category	DfS-Developed
shipped in	wet ice
storage temp.	−20°C
target post-translational modification	unmodified
Gene Information	human ... UNG(7374)

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