Anti-GCLC antibody produced in rabbit,100UL,SAB5700670-100UL,Sigma

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订货号 0BN7333
品牌型号 Sigma SAB5700670-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction.


Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-252 of human GCLC (NP_001489.1).


Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.


Preparation Note

Store at -20℃. Avoid freeze / thaw cycles.


技术参数 Specifications
biological sourcerabbit
Quality Level100
conjugateunconjugated
antibody formaffinity isolated antibody
antibody product typeprimary antibodies
clonepolyclonal
formbuffered aqueous solution
mol wt 72
species reactivityhuman, mouse, rat
concentration0.85 mg/ml
technique(s)western blot: 1:500-1:2000
UniProt accession no.P48506
shipped inwet ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... GCLC(2729)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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