- 商品介绍
- 规格参数
- 包装参数
Application
Protein Kinase G is a serine/threonine-specific protein kinase that is activated by cGMP. Protein Kinase G Iβ is used to induce apoptosis and inhibit cell proliferation.
Biochem/physiol Actions
Protein Kinase G Iβ induces apoptosis in certain cell lines such as human breast cancer cell lines MCF-7 and MDA-MB-468. It inhibits cell proliferation and induces apoptosis in colon cancer cell lines.
Physical form
Solution in 20 mM Tris buffer, pH 7.4, 1 mM EDTA, 1 mM β-mercaptoethanol, 100 mM NaCl, 10 U/ml Trasylol, and 50% glycerol.
Other Notes
One unit will phosphorylate 1 micromole of VASPtide(RRKVSKQE) substrate per minute in 10 mM HEPES, pH 7.4, 5 mM MgCl2, 1 mM DTE and 0.2 mM EDTA.
| recombinant | expressed in baculovirus infected Sf9 cells |
| Quality Level | 200 |
| assay | ≥95% (SDS-PAGE) |
| form | buffered aqueous glycerol solution |
| specific activity | ≥1.5 units/mg protein (20-fold stimulation by cGMP (5 μM)) |
| mol wt | 76 kDa (monomer) |
| UniProt accession no. | Q13976 |
| relevant disease(s) | cancer |
| shipped in | wet ice |
| storage temp. | −20°C |
| Gene Information | human ... PRKG1(5592) |
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瓶顶过滤器-500ml容量,MF75TM系列，聚苯乙烯外壳，75mmPES滤膜，孔径0.45um,适合瓶颈尺寸33mm，12/箱，295-3345，Nalgene，Thermofisher，赛默飞世尔¥ 775.42
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