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Biochem/physiol Actions
Arylquin 1 is a potent secretagogue of the tumor suppressor protein prostate apoptosis response-4 (Par-4), selectively inducing apoptosis in a variety of cancer cells. Arylquin 1 acts by binding to vimentin, displacing Par-4 from vimentin for secretion. Arylquin 1 produced a dose-dependent secretion of Par-4 at nanomolar concentrations.
Arylquin 1 is a potent secretagogue of the tumor suppressor protein prostate apoptosis response-4 (Par-4).
| Quality Level | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| color | , white to yellow to light brown |
| solubility | DMSO: 20 mg/mL, clear |
| storage temp. | 2-8°C |
| SMILES string | NC1=NC2=CC(N(C)C)=CC=C2C=C1C3=CC=CC=C3F |
| InChI | 1S/C17H16FN3/c1-21(2)12-8-7-11-9-14(17(19)20-16(11)10-12)13-5-3-4-6-15(13)18/h3-10H,1-2H3,(H2,19,20) |
| InChI key | RHAQINSYYSNKKI-UHFFFAOYSA-N |
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¥ 2622.09
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¥ 2290.21
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¥ 2013.69
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¥ 1451.54
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¥ 1476.00
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