Anti-Plectin Antibody, clone 9O0B3, Rabbit Monoclonal，100UL，SAB5702939-100UL，Sigma 供应商、价格、厂家、报价、规格参数

产品介绍 Product Description

General description

Plectin is a prominent member of an important family of structurally and in part functionally related proteins, termed plakins or cytolinkers, that are capable of interlinking different elements of the cytoskeleton. Plakins, with their multi-domain structure and enormous size, not only play crucial roles in maintaining cell and tissue integrity and orchestrating dynamic changes in cytoarchitecture and cell shape, but also serve as scaffolding platforms for the assembly, positioning, and regulation of signaling complexes. Plectin is expressed as several protein isoforms in a wide range of cell types and tissues. As the expression of specific plectin isoforms was found to be dependent on cell type (tissue) and stage of development it appears that each cell type (tissue) contains a unique set (proportion and composition) of plectin isoforms, as if custom-made for specific requirements of the particular cells. Two other subtypes of plectin-related EBS have been described: EBS-pyloric atresia (PA) and EBS-Ogna.

Immunogen

PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Recombinant fusion protein containing a sequence corresponding to amino acids 4401-4609 of human Plectin (NP_958782.1).

Application

IHC

技术参数 Specifications

biological source	rabbit
Quality Level	100
conjugate	unconjugated
material	colorless
clone	9O0B3, monoclonal
form	liquid
species reactivity	rat, human
concentration	1.20 mg/mL
technique(s)	immunohistochemistry: 1:50 - 1:200
color	colorless
isotype	IgG
immunogen sequence	RTQLASWSDPTEETGPVAGILDTETLEKVSITEAMHRNLVDNITGQRLLEAQACTGGIIDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALKKGWLYYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEALQRGTVDARTAQKLRDVGAYSKYLTCPKTKLKISYKDALDRSMVEEGTGLRLLEAAAQSTK
UniProt accession no.	Q15149
shipped in	wet ice
storage temp.	−20°C
target post-translational modification	unmodified
Gene Information	human ... PLEC(5339)

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