Anti-PI3KC2A (N-term) antibody produced in rabbit,100UG,SAB1300024-100UG,Sigma

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订货号 0BN4860
品牌型号 Sigma SAB1300024-100UG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

PI3KC2A belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is not sensitive to nanomolar levels of the inhibitor wortmanin. This protein was shown to be able to be activated by insulin and may be involved in integrin-dependent signaling.


Immunogen

PI3KC2A (NP_002636, 13-46)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human PI3KC2A.


Physical form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.


技术参数 Specifications
biological sourcerabbit
Quality Level200
conjugateunconjugated
antibody formIgG fraction of antiserum
antibody product typeprimary antibodies
clonepolyclonal
formbuffered aqueous solution
species reactivityhuman
technique(s)indirect ELISA: 1:1000,western blot: 1:100-1:500
NCBI accession no.NP_002636
UniProt accession no.O00443
shipped indry ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... PIK3C2A(5286)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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