- 商品介绍
- 规格参数
- 包装参数
Application
Detomidine may be used in the research field foranimal behavior studies to facilitate sedation and to conduct procedures thatneed immobilization of animals for observation.
Biochem/physiol Actions
Detomidine is an α2-adrenergic receptor(α2-adrenoceptor) agonist with in vivo sedative and analgesic efficacy.In receptor binding experiments, detomidine showed strong affinity to alpha2-receptors. There was some binding affinity towards alpha 1-receptors also butonly negligible or no affinity towards dopamine, opiate and adenosinereceptors. Detomidine is a derivative of imidazole that exerts muscle relaxation effects. It also acts as an anesthetic adjunct. Detomidine also shows cardiovascular effectssuch as induction of a state of hypertension, bradycardia and increasedsystemic and pulmonary vascular resistance.(4)
| Quality Level | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| color | white to beige |
| solubility | DMSO: 2 mg/mL, clear |
| storage temp. | -10 to -25°C |
| SMILES string | CC1=C(C=CC=C1C)CC2=CN=CN2 |
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