- 商品介绍
- 规格参数
- 包装参数
Biochem/physiol Actions
T3MG is a selective inhibitor of excitatory amino acid transporters GLT-1, EAAT2, and EAAT4.
T3MG is a selective inhibitor of excitatory amino acid transporters GLT-1, EAAT2, and EAAT4. T3MG has long been utilized as a gold standard in the study of general EAAT function. It has more recently been shown to be selective for EAAT2 and EAAT4 as compared to EAAT1 and EAAT3 in electrophysiology and glutamate/aspartate uptake assays. Although there are other EAAT2-selective compounds, this is the first tool with selectivity for EAAT4. T3MG is not a substrate for the transporters themselves, nor does it have activity at glutamate ion channels.
Features and Benefits
This compound is featured on the Excitatory Amino Acid Transporters page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Preparation Note
T3MG dissolves in water at a concentration that is greater than 1.5 mg/ml.
| form | powder |
| Quality Level | 100 |
| color | white to off-white |
| solubility | H2O: >1.5 mg/dL |
| suitability | suitable for TLC (single spot) |
| storage temp. | room temp |
| SMILES string | C[C@@H](CC(O)=O)[C@@H](N)C(O)=O |
| InChI | 1S/C6H11NO4/c1-3(2-4(8)9)5(7)6(10)11/h3,5H,2,7H2,1H3,(H,8,9)(H,10,11)/t3-,5+/m0/s1 |
| InChI key | FHJNAFIJPFGZRI-WVZVXSGGSA-N |
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¥ 12156.68
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¥ 1451.54
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¥ 3442.25
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¥ 2883.61
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无菌，PETG 方形有刻度培养基瓶，带盖，聚对苯二酸乙二醇酯共聚物，天然高密度聚乙烯盖，500毫升容量，每箱40，40/箱，342020-0500，Nalgene，Thermofisher，赛默飞世尔¥ 3684.34
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