非那雄胺,100MG,F1293-100MG,Sigma

销售价: ¥ 722.83 / 件
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订货号 0BN4578
品牌型号 Sigma F1293-100MG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

Application

Finasteride has been used:

  • as a component of L-15 media to investigate the effects of finasteride exposure on brain, liver and testis tissues
  • in culture medium to treat tumor cells in vitro
  • as a positive control to treat benign prostatic hyperplasia (BPH)
  • to examine its effect on structural and molecular biology on the ventral prostate of senile mice


Biochem/physiol Actions

Finasteride can reduce serum and scalp dihydrotestosterone (DHT) by preventing the transformation of testosterone to DHT. It is usually used to manage benign prostate hyperplasia and pattern hair loss in male. Finasteride possesses androgen-distracting properties.
选择性 5α-还原酶抑制剂;抗雄激素。


技术参数 Specifications
Quality Level100
assay≥98% (HPLC)
formpowder
color white to beige
solubilityDMSO: soluble >20 mg/mL
web metadata keyword.defaultACS grade finasteride,MK-906 finasteride for laboratory use,N-(2-methyl-2-propyl)-3-oxo-4-aza-5α-androst-1-ene-17β-carboxamide,finasteride CAS 98319-26-7,finasteride L-15 media component,finasteride SRD5A1 SRD5A2 inhibitors,finasteride Sigma-Aldrich 10mg,finasteride as positive control for BPH,finasteride for DHT reduction studies,finasteride for in vitro tumor cell treatment,finasteride high purity research chemical,finasteride structural biology research,finasteride treatment for senile mice research,finasteride
storage temp.room temp
SMILES string[H][C@@]12CC[C@@]3([H])[C@]4([H])CC[C@H](C(=O)NC(C)(C)C)[C@@]4(C)CC[C@]3([H])[C@@]1(C)C=CC(=O)N2
InChI1S/C23H36N2O2/c1-21(2,3)25-20(27)17-8-7-15-14-6-9-18-23(5,13-11-19(26)24-18)16(14)10-12-22(15,17)4/h11,13-18H,6-10,12H2,1-5H3,(H,24,26)(H,25,27)/t14-,15-,16-,17+,18+,22-,23+/m0/s1
InChI keyDBEPLOCGEIEOCV-WSBQPABSSA-N
Gene Informationhuman ... HSD3B1(3283), SRD5A1(6715), SRD5A2(6716)
rat ... Hsd3b1(360348), Srd5a1(24950), Srd5a2(64677)
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