- 商品介绍
- 规格参数
- 包装参数
General description
SILu™Lite IL8 is a recombinant human protein expressed in human 293 cells. It is a mixture of the 3 main CXCL8 isoforms with the molecular weights, amino acid number and relative abundance as described in Table 1 of the product datasheet. SILu™Lite IL8 is an analytical standard designed to be used as starting material for preparation of calibrators and controls in LC-MS applications.
Biochem/physiol Actions
Interleukin-8 (IL-8) is a member of the CXC chemokine subfamily and is produced by blood cells and many types of tissues. The measurement of IL-8 in voided urinary samples may have utility for urine-based detection of bladder cancer. Urinary IL-8 was a strong biomarker of stress under intensive and prolonged demands, both acutely and over time. IL-8 and cathepsin B levels were significantly elevated in melanoma patients, and more importantly, the combination of IL-8 and cathepsin B were also studied as a prognosis marker for melanoma mortality.
Physical form
Supplied as a lyophilized powder containing phosphate buffered saline.
Other Notes
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Legal Information
SILu is a trademark of Sigma-Aldrich Co. LLC
| recombinant | expressed in HEK 293 cells |
| Quality Level | 200 |
| assay | ≥95% (SDS-PAGE) |
| form | lyophilized powder |
| suitability | suitable for mass spectrometry (internal calibrator) |
| UniProt accession no. | P10145 |
| shipped in | ambient |
| storage temp. | −20°C |
| Gene Information | human ... CXCL8(3576) |
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