LAG-3 (mouse): FC (mouse),50UG,SRP8041-50UG,Sigma

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订货号 : 0BN3910
品牌型号 : Sigma SRP8041-50UG
货期 : 询货期
最小订货量 : 1件
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产品介绍 Product Description

General description

Lymphocyte activation gene 3 (LAG-3; CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4.


Physical form

Solution in PBS.


Other Notes

The sequence coding for the 4 extracellular Ig-like domains of mouse LAG-3 (D1-D4) is fused to the Fc portion of mouse IgG2a (hinge-CH2-CH3).


技术参数 Specifications
biological sourcemouse
recombinantexpressed in CHO cells
assay>95% (SDS-PAGE)
formliquid
mol wtmonomer ~180 kDa by SDS-PAGE (non-reducing),monomer ~80 kDa by SDS-PAGE (reducing)
packagingpkg of 50 μg
storage conditionavoid repeated freeze/thaw cycles
concentration≥0.2 mg/mL
impurities<1 EU/μg endotoxin, tested
colorclear
UniProt accession no.Q61790
shipped inwet ice
storage temp.−20°C
Gene Informationmouse ... Lag3(16768)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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