- 商品介绍
- 规格参数
- 包装参数
产品介绍
Product Description
General description
Lymphocyte activation gene 3 (LAG-3; CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4.
Physical form
Solution in PBS.
Other Notes
The sequence coding for the 4 extracellular Ig-like domains of mouse LAG-3 (D1-D4) is fused to the Fc portion of mouse IgG2a (hinge-CH2-CH3).
技术参数
Specifications
| biological source | mouse |
| recombinant | expressed in CHO cells |
| assay | >95% (SDS-PAGE) |
| form | liquid |
| mol wt | monomer ~180 kDa by SDS-PAGE (non-reducing),monomer ~80 kDa by SDS-PAGE (reducing) |
| packaging | pkg of 50 μg |
| storage condition | avoid repeated freeze/thaw cycles |
| concentration | ≥0.2 mg/mL |
| impurities | <1 EU/μg endotoxin, tested |
| color | clear |
| UniProt accession no. | Q61790 |
| shipped in | wet ice |
| storage temp. | −20°C |
| Gene Information | mouse ... Lag3(16768) |
| 长度(mm) | |
| 宽度(mm) | |
| 高度(mm) | |
| 重量(kg) |
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