Anti-A1CF antibody produced in mouse,50UG,SAB1400523-50UG,Sigma

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订货号 0BN2479
品牌型号 Sigma SAB1400523-50UG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

Mammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. The gene product has three non-identical RNA recognition motifs and belongs to the hnRNP R family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events. Alternative splicing occurs at this locus and three full-length transcript variants, encoding three distinct isoforms, have been described. Additional splicing has been observed but the full-length nature of these variants has not been determined. (provided by RefSeq)


Immunogen

A1CF (NP_620311.1, 1 a.a. ~ 594 a.a) full-length human protein.

Sequence
MEAVCLGTCPEPEASMSTAIPGLKKGNNALQSIILQTLLEKENGQRKYGGPPPGWDAAPPERGCEIFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQLNNYEIRNGRLLGVCASVDNCRLFVGGIPKTKKREEILSEMKKVTEGVVDVIVYPSAADKTKNRGFAFVEYESHRAAAMARRKLLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKILYVRNLMLSTSEEMIEKEFNNIKPGAVERVKKIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAKPVDKDSYVRYTRGTGGRGTMLQGEYTYSLGQVYDPTTTYLGAPVFYAPQTYAAIPSLHFPATKGHLSNRAIIRAPSVRGAAGVRGLGGRGYLAYTGLGRGYQVKGDKREDKLYDILPGMELTPMNPVTLKPQGIKLAPQILEEICQKNNWGQPVYQLHSAIGQDQRQLFLYKITIPALASQNPAIHPFTPPKLSAFVDEAKTYAAEYTLQTLGIPTDGGDGTMATAAAAATAFPGYAVPNATAPVSAAQLKQAVTLGQDLAAYTTYEVYPTFAVTARGDGYGTF


Physical form

Solution in phosphate buffered saline, pH 7.4


技术参数 Specifications
biological sourcemouse
Quality Level100
conjugateunconjugated
antibody formIgG fraction of antiserum
antibody product typeprimary antibodies
clonepolyclonal
formbuffered aqueous solution
species reactivityhuman
technique(s)immunofluorescence: suitable,western blot: 1 μg/mL
UniProt accession no.Q9NQ94
shipped indry ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... A1CF(29974)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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