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- 规格参数
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General description
This ELISA antibody pair detects Human Galectin-8 (LGALS8)
Application
For research use only. Not for use in diagnostic procedures.
Please refer to the attached Protocolfor details.
Biochem/physiol Actions
Galectin-8 (Gal-8) is a member of “tandem-repeat” galectin family, possesses two carbohydrate binding domains linked by a short peptide. The short peptide accounts for Gal-8 cell adhesion and downstream signalling. Tumor cells, as well as normal tissues, express Gal-8. The expression level of Gal-8 is higher in multiple myeloma conditions and enhances adhesion to vascular endothelium. Galectin-8 binds to integrin selectively and inhibits cell adhesion and promotes apoptosis. Gal-8 interacts with integrin alpha and regulates neutrophil adhesion to endothelial cells and migration. Gal-8 ligand binds to cluster of differentiation 44 (CD44) and causes an inflammatory response in rheumatoid arthritis. Overexpression of Gal-8 plays a key role in metastasis of prostate cancer and cell survival by causing rearrangement of the cytoskeleton and E-cadherin expression.
Other Notes
A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number.
| species reactivity | human |
| packaging | kit of 96 wells (12 strips x 8 wells) |
| technique(s) | ELISA: suitable |
| input | sample type plasma sample type serum sample(s) sample type cell culture supernatant(s) |
| assay range | inter-assay cv: <12% intra-assay cv: <10% sensitivity: 0.16 ng/ml |
| detection method | colorimetric |
| shipped in | wet ice |
| storage temp. | −20°C |
| Gene Information | human ... LGALS8(3964) |
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询价
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¥ 807.83
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¥ 1243.80
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¥ 3593.05
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¥ 907.59
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¥ 713.29
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¥ 634.68
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¥ 839.71
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询价
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¥ 1790.42
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¥ 1464.96
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