Anti-Human IgG3 Antibody, clone 6Q4J8, Rabbit Monoclonal，100UL，SAB5702173-100UL，Sigma 供应商、价格、厂家、报价、规格参数

产品介绍 Product Description

General description

Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens. The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen.

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 50-150 of human IgG3 (P01860).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Application

WB

技术参数 Specifications

biological source	rabbit
Quality Level	100
conjugate	unconjugated
material	colorless
clone	6Q4J8, monoclonal
form	liquid
mol wt	60 kDa
species reactivity	human, rat
concentration	0.5 mg/mL
technique(s)	western blot: 1:500 - 1:2000
color	colorless
isotype	IgG
immunogen sequence	VHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYTCNVNHKPSNTKVDKRVELKTPLGDTTHTCPRCPEPKSCDTPPPCPRCPEPKSCDTPPPCPRCPEPKSC
UniProt accession no.	P01860
shipped in	wet ice
storage temp.	−20°C
target post-translational modification	unmodified
Gene Information	human ... IGHG3(3502)

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