- 商品介绍
- 规格参数
- 包装参数
Biochem/physiol Actions
Alvimopan is a gastroprokinetic peripheral mu-opioid receptor antagonist.
Alvimopan is a gastroprokinetic peripheral mu-opioid receptor antagonist. As a drug, Alvimopan is given to patients undergoing bowel surgery to protect the bowel from the effects of opioid medications that are used to treat pain, blocking the undesirable GI side-effects of the opioid agonists without affecting analgesia or causing withdrawal. Alvimopan does not cross the blood-brain barrier, competitively binding to gastrointestinal tract mu-opioid receptors.
| Quality Level | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| optical activity | [α]/D +46 to +52°, c = 1.0 in DMSO |
| color | white to beige |
| solubility | DMSO: 10 mg/mL, clear |
| storage temp. | 2-8°C |
| SMILES string | C[C@H]1CN(C[C@@H](C(NCC(O)=O)=O)CC2=CC=CC=C2)CC[C@]1(C3=CC=CC(O)=C3)C |
| InChI | 1S/C25H32N2O4/c1-18-16-27(12-11-25(18,2)21-9-6-10-22(28)14-21)17-20(24(31)26-15-23(29)30)13-19-7-4-3-5-8-19/h3-10,14,18,20,28H,11-13,15-17H2,1-2H3,(H,26,31)(H,29,30)/t18-,20-,25+/m0/s1 |
| InChI key | UPNUIXSCZBYVBB-JVFUWBCBSA-N |
| Gene Information | human ... OPRM1(4988) |
| 长度(mm) | |
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| 重量(kg) |
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