- 商品介绍
- 规格参数
- 包装参数
Biochem/physiol Actions
CMPPE is a GABAB receptor positive allosteric modulator (PAM).
CMPPE is a GABAB receptor positive allosteric modulator (PAM). GABAB receptor positive allosteric modulators have potential for treatment of many neuro-psychiatric disorders as well as drug dependence and seizures. The receptor is a GPCR expressed throughout the CNS; it acts as both an auto-receptor and heteroreceptor to mudulate GABA release and regulate K+ channels and Ca++ channels. CMPPE has the highest hypoactivity/anticonvulsant ratio.
| Quality Level | 100 |
| assay | ≥95% (HPLC) |
| form | powder |
| color | white to light brown |
| solubility | DMSO: 5 mg/mL, clear (warmed) |
| storage temp. | 2-8°C |
| SMILES string | ClC(C=C1)=CC=C1C2=NN(C(N3C(CCO)CCCC3)=CC(C)=N4)C4=C2 |
| InChI | 1S/C20H23ClN4O/c1-14-12-20(24-10-3-2-4-17(24)9-11-26)25-19(22-14)13-18(23-25)15-5-7-16(21)8-6-15/h5-8,12-13,17,26H,2-4,9-11H2,1H3 |
| InChI key | TZWSGOPCLUTFBZ-UHFFFAOYSA-N |
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¥ 1082.93
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¥ 1669.50
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¥ 2355.14
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¥ 1987.51
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