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Biochem/physiol Actions
A71915 is a potent atrial natriuretic peptide A (ANP, NPPA) receptor (NPR1, ANP-A, ANPR-A, NPR-A) antagonist (pKi = 9.18 (Ki = 650 nM) by competitive binding against 300 nM rat ANP1-28 to human neuroblastoma NB-OK-1 cells; pA2 = 9.45 against rat ANP-induced cGMP production in NB-OK-1 cells). A71915 is reactive toward dog, human, mouse, rabbit, and rat species, and commonly employed both in cultures (1-10 μM) and in vivo for studying NPR-A-mediated responses.
Atrial natriuretic peptide A (ANP, NPPA) receptor (NPR1, ANPRA, NPRA) antagonist with in vitro and in vivo efficacy.
| Quality Level | 100 |
| assay | ≥95% (HPLC) |
| form | powder |
| color | white to off-white |
| storage temp. | −20°C |
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¥ 4862.67
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¥ 1048.84
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¥ 1125.70
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¥ 3683.17
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¥ 4110.85
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¥ 502.32
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¥ 699.66
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¥ 590.56
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¥ 64659.66
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¥ 165230.53
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¥ 51018.02
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