Anti-TIMP2 antibody produced in rabbit,100UL,SAB5700746-100UL,Sigma

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订货号 0BM6315
品牌型号 Sigma SAB5700746-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix.


Immunogen

A synthetic peptide corresponding to a sequence within amino acids 100-200 of human TIMP2 (NP_003246.1).


Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.


Preparation Note

Store at -20℃. Avoid freeze / thaw cycles.


技术参数 Specifications
biological sourcerabbit
Quality Level100
conjugateunconjugated
antibody formaffinity isolated antibody
antibody product typeprimary antibodies
clonepolyclonal
formbuffered aqueous solution
mol wt 24
species reactivitymouse, human, rat
concentration1.81 mg/ml
technique(s)immunofluorescence: 1:50-1:200,western blot: 1:500-1:2000
UniProt accession no.P16035
shipped inwet ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... TIMP2(7077)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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