Anti-Rad18 Antibody, clone 9Y1H3, Rabbit Monoclonal,100UL,SAB5702376-100UL,Sigma

销售价: ¥ 3636.13 / 件
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订货号 0BM5755
品牌型号 Sigma SAB5702376-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens. [provided by RefSeq, Jul 2008]


Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Rad18 (Q9NS91).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.


Application

WB


技术参数 Specifications
biological sourcerabbit
Quality Level100
conjugateunconjugated
materialcolorless
clone9Y1H3, monoclonal
formliquid
species reactivityrat, human
concentration0.15 mg/mL
technique(s)western blot: 1:500 - 1:2000
color colorless
isotypeIgG
immunogen sequenceMDSLAESRWPPGLAVMKTIDDLLRCGICFEYFNIAMIIPQCSHNYCSLCIRKFLSYKTQCPTCCVTVTEPDLKNNRILDELVKSLNFARNHLLQFALESP
UniProt accession no.Q9NS91
shipped inwet ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... RAD18(56852)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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