Monoclonal Anti-HAX1 antibody produced in mouse,100UG,SAB1404830-100UG,Sigma

销售价: ¥ 4046.38 / 件
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订货号 0BM5250
品牌型号 Sigma SAB1404830-100UG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

The protein encoded by this gene is known to associate with hematopoietic cell-specific Lyn substrate 1, a substrate of Src family tyrosine kinases. It also interacts with the product of the polycystic kidney disease 2 gene, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with the F-actin-binding protein, cortactin. It was earlier thought that this gene product is mainly localized in the mitochondria, however, recent studies indicate it to be localized in the cell body. Mutations in this gene result in autosomal recessive severe congenital neutropenia, also known as Kostmann disease. Two transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq)


Immunogen

HAX1 (NP_006109.2, 76 a.a. ~ 174 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
HDNFGFDDLVRDFNSIFSDMGAWTLPSHPPELPGPESETPGERLREGQTLRDSMLKYPDSHQPRIFGGVLESDARSESPQPAPDWGSQRPFHRFDDVWP


Physical form

Solution in phosphate buffered saline, pH 7.4


Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


技术参数 Specifications
biological sourcemouse
Quality Level100
conjugateunconjugated
antibody formpurified immunoglobulin
antibody product typeprimary antibodies
clone1D2, monoclonal
formbuffered aqueous solution
mol wtantigen ~37 kDa
species reactivityhuman
technique(s)capture ELISA: suitable,indirect ELISA: suitable,western blot: 1-5 μg/mL
isotypeIgG2aκ
NCBI accession no.NM_006118
UniProt accession no.O00165
shipped indry ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... HAX1(10456)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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