Monoclonal Anti-Notch1 - Percp antibody produced in mouse，100UG，SAB5200921-100UG，Sigma 供应商、价格、厂家、报价、规格参数

产品介绍 Product Description

General description

The NOTCH1 gene is mapped to human chromosome 9q34.3. In mice, Notch1 is highly expressed in immature neurons of hippocampus. Notch1 is localized to renal epithelial cells and podocytes of metanephros.

Immunogen

Fusion protein amino acids 20-216 (extracellular N-terminus, EGF-like domains 1-5) of mouse Notch1

Biochem/physiol Actions

The Notch signaling pathway regulates endothelial-cell differentiation, proliferation and apoptosis, and is essential for the development, maintenance and remodeling of the vascular system. Notch signaling pathway is involved in the development and progress of cardiovascular diseases. Notch1 function is predominant in developing kidney compared to compared to the mature organ.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

PBS pH7.4, 50% glycerol, 0.09% sodium azide

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

技术参数 Specifications

biological source	mouse
Quality Level	100
conjugate	Peridinin-Chlorophyll-Protein Complex
antibody form	purified immunoglobulin
antibody product type	primary antibodies
clone	S253-32, monoclonal
form	buffered aqueous solution
mol wt	antigen predicted mol wt >270, ~120 kDa
species reactivity	mouse, rat, human
concentration	1 mg/mL
technique(s)	immunocytochemistry: suitable,western blot: suitable
isotype	IgG1
NCBI accession no.	NP_032740.3
UniProt accession no.	Q07008
shipped in	wet ice
storage temp.	−20°C
target post-translational modification	unmodified
Gene Information	mouse ... Notch1(18128)

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