Momordin Ιc,5MG,SML3435-5MG,Sigma

销售价: ¥ 550.21 / 件
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订货号 0BM3352
品牌型号 Sigma SML3435-5MG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

Momordin Ιc is a pentacyclic triterpenoid isolated from Kochia scoparia (L.) fruit and other medicinal plants.


Biochem/physiol Actions

Momordin Ic is a potent inhibitor of SUMO-specific protease 1 (SENP1) that increases SUMOylated proteins in PC3 cells. It inhibits cell proliferation and induces cell death in prostate cancer PC3 xenograft mouse model. Momordin Ιc decreases serum glucose and ethanol levels after oral administration through acceleration of gastrointestinal transit.


技术参数 Specifications
Quality Level100
assay≥98% (HPLC)
formpowder
optical activity[α]/D 12 to 17° in methanol (c=0.5 g/100mL)
color white to beige
solubilityDMSO: 2 mg/mL, clear
storage temp.-10 to -25°C
SMILES stringO1[C@H]([C@@H]([C@H]([C@@H]([C@H]1C(=O)O)O)O[C@@H]7OC[C@H]([C@@H]([C@H]7O)O)O)O)O[C@@H]2C([C@H]3[C@@]([C@@H]4[C@]([C@@]5(CC[C@@]6([C@@H](CC(CC6)(C)C)C5=CC4)C(=O)O)C)(CC3)C)(CC2)C)(C)C
InChI1S/C41H64O13/c1-36(2)14-16-41(35(49)50)17-15-39(6)20(21(41)18-36)8-9-24-38(5)12-11-25(37(3,4)23(38)10-13-40(24,39)7)52-34-29(46)30(28(45)31(54-34)32(47)48)53-33-27(44)26(43)22(42)19-51-33/h8,21-31,33-34,42-46H,9-19H2,1-7H3,(H,47,48)(H,49,50)/t21-,22+,23-,24+,25-,26-,27+,28-,29+,30-,31-,33-,34+,38-,39+,40+,41-/m0/s1
InChI keyHWYBGIDROCYPOE-WEAQAMGWSA-N
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