- 商品介绍
- 规格参数
- 包装参数
产品介绍
Product Description
General description
Momordin Ιc is a pentacyclic triterpenoid isolated from Kochia scoparia (L.) fruit and other medicinal plants.
Biochem/physiol Actions
Momordin Ic is a potent inhibitor of SUMO-specific protease 1 (SENP1) that increases SUMOylated proteins in PC3 cells. It inhibits cell proliferation and induces cell death in prostate cancer PC3 xenograft mouse model. Momordin Ιc decreases serum glucose and ethanol levels after oral administration through acceleration of gastrointestinal transit.
技术参数
Specifications
| Quality Level | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| optical activity | [α]/D 12 to 17° in methanol (c=0.5 g/100mL) |
| color | white to beige |
| solubility | DMSO: 2 mg/mL, clear |
| storage temp. | -10 to -25°C |
| SMILES string | O1[C@H]([C@@H]([C@H]([C@@H]([C@H]1C(=O)O)O)O[C@@H]7OC[C@H]([C@@H]([C@H]7O)O)O)O)O[C@@H]2C([C@H]3[C@@]([C@@H]4[C@]([C@@]5(CC[C@@]6([C@@H](CC(CC6)(C)C)C5=CC4)C(=O)O)C)(CC3)C)(CC2)C)(C)C |
| InChI | 1S/C41H64O13/c1-36(2)14-16-41(35(49)50)17-15-39(6)20(21(41)18-36)8-9-24-38(5)12-11-25(37(3,4)23(38)10-13-40(24,39)7)52-34-29(46)30(28(45)31(54-34)32(47)48)53-33-27(44)26(43)22(42)19-51-33/h8,21-31,33-34,42-46H,9-19H2,1-7H3,(H,47,48)(H,49,50)/t21-,22+,23-,24+,25-,26-,27+,28-,29+,30-,31-,33-,34+,38-,39+,40+,41-/m0/s1 |
| InChI key | HWYBGIDROCYPOE-WEAQAMGWSA-N |
| 长度(mm) | |
| 宽度(mm) | |
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| 重量(kg) |
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