- 商品介绍
- 规格参数
- 包装参数
Biochem/physiol Actions
ABC1183 is an orally active, potent and selective inhibitor of GSK3 α/β and CDK9, which induces G2/M cell cycle arrest and apoptosis in cancer cells. Apparently ABC1183 suppresses tumor growth and inflammation-driven gastrointestinal disease symptoms due to down regulation of TNFα and IL-6 pro-inflammatory cytokines. It does not exhibit organ or hematological toxicities.
an orally active, potent and selective inhibitor of GSK3 α/β and CDK9
| assay | ≥98% (HPLC) |
| form | powder |
| color | white to beige |
| solubility | DMSO: 2 mg/mL, clear |
| storage temp. | 2-8°C |
| SMILES string | NC1=C(C(C2=CC=C(C=C2)C#N)=O)SC(NC3=CC=C(C)C=C3)=N1 |
| InChI | 1S/C18H14N4OS/c1-11-2-8-14(9-3-11)21-18-22-17(20)16(24-18)15(23)13-6-4-12(10-19)5-7-13/h2-9H,20H2,1H3,(H,21,22) |
| InChI key | CUDLEXBIVZPJBU-UHFFFAOYSA-N |
| 长度(mm) | |
| 宽度(mm) | |
| 高度(mm) | |
| 重量(kg) |
-
询价
-
询价
-
询价
-
询价
-
询价
-
¥ 3275.78
-
询价
-
¥ 4897.21
-
询价
-
¥ 2882.02
-
¥ 1564.00
-
¥ 787.34
-
¥ 2452.91
-
¥ 2406.69
-
¥ 1351.48
-
¥ 2888.88
-
¥ 18741.69
-
¥ 65710.50
-
¥ 3704.60
-
¥ 15894.19
微信小程序
7X24小时在线咨询