Monoclonal Anti-ATP7B antibody produced in mouse,100UG,WH0000540M1-100UG,Sigma

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订货号 : 0BM2261
品牌型号 : Sigma WH0000540M1-100UG
货期 : 询货期
最小订货量 : 1件
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产品介绍 Product Description

General description

This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein functions as a monomer, exporting copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease (WD). (provided by RefSeq)


Immunogen

ATP7B (NP_000044, 1372 a.a. ~ 1465 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
QLKCYKKPDLERYEAQAHGHMKPLTASQVSVHIGMDDRWRDSPRATPWDQVSYVSQVSLSSLTSDKPSRHSAAADDDGDKWSLLLNGRDEEQYI


Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.


Physical form

Solution in phosphate buffered saline, pH 7.4


Legal Information

GenBank is a registered trademark of United States Department of Health and Human Services


技术参数 Specifications
biological sourcemouse
Quality Level100
conjugateunconjugated
antibody formpurified immunoglobulin
antibody product typeprimary antibodies
clone3E10, monoclonal
formbuffered aqueous solution
species reactivityhuman
technique(s)ELISA: suitable,western blot: 1-5 μg/mL
isotypeIgG1κ
GenBank accession no.NM_000053
UniProt accession no.P35670
shipped indry ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... ATP7B(540)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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