Monoclonal Anti-TWIST2 antibody produced in mouse,100UG,WH0117581M1-100UG,Sigma

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订货号 0BM2232
品牌型号 Sigma WH0117581M1-100UG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

Twist family bHLH transcription factor 2 (TWIST2) is part of the basic helix-loop-helix protein (bHLH) family. It acts as a molecular switch by activating or repressing target genes. The TWIST2 gene is localized on human chromosome 2q37.3.


Immunogen

TWIST2 (AAH33168, 1 a.a. ~ 160 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
MEEGSSSPVSPVDSLGTSEEELERQPKRFGRKRRYSKKSSEDGSPTPGKRGKKGSPSAQSFEELQSQRILANVRERQRTQSLNEAFAALRKIIPTLPSDKLSKIQTLKLAARYIDFLYQVLQSDEMDNKMTSCSYVAHERLSYAFSVWRMEGSWSMSASH


Application

Monoclonal Anti-TWIST2 antibody produced in mouse has been used in immunohistochemistry.


Biochem/physiol Actions

Twist family bHLH transcription factor 2 (TWIST2) modulates transcription in mesenchymal cell lineages during development. It interacts with E-protein modulators and binds with E-box on DNA sequences. Mutations in the TWIST2 gene have been linked with Setleis syndrome.


Physical form

Solution in phosphate buffered saline, pH 7.4


Legal Information

GenBank is a registered trademark of United States Department of Health and Human Services


Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


技术参数 Specifications
biological sourcemouse
Quality Level100
conjugateunconjugated
antibody formpurified immunoglobulin
antibody product typeprimary antibodies
clone3C8, monoclonal
formbuffered aqueous solution
species reactivityhuman
technique(s)immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable,indirect ELISA: suitable,western blot: 1-5 μg/mL
isotypeIgG1κ
GenBank accession no.BC033168
UniProt accession no.Q8WVJ9
application(s)research pathology
shipped indry ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... TWIST2(117581)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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