- 商品介绍
- 规格参数
- 包装参数
General description
The antibody will neutralize human cell surface CXCR-2 mediated-myloperoxidase release from human granulocytes induced by GROα. It will not block myeloperoxidase release induced by IL-8. The antibody reacts with human CXCR-2 transfectant cells and not the parent cell line. The antibody shows no cross-reactivity with CXCR-1.
Immunogen
human CXCR2 transfected NSO mouse myeloma cells.
Biochem/physiol Actions
CXCR2 is a G protein-coupled receptor that binds IL-8 with high affinity. It mediates migration of neutrophils to the sites of inflammation. It also binds CXCL1 and stimulates growth of melanomas.
Physical form
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing carbohydrates.
Preparation Note
Purified using protein G.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | mouse |
| Quality Level | 100 |
| conjugate | unconjugated |
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone | 48311, monoclonal |
| form | lyophilized powder |
| species reactivity | human |
| technique(s) | flow cytometry: suitable,neutralization: suitable |
| isotype | IgG2a |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human ... IL8RB(3579) mouse ... Il8rb(12765) |
| 长度(mm) | |
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