- 商品介绍
- 规格参数
- 包装参数
产品介绍
Product Description
Biochem/physiol Actions
PF-04957325 is a cAMP-competitive, potent and selective phosphodiesterase 8 inhibitor (IC50 = 3.05 nM/PDE8A, 0.44 nM/PDE8B, 1 μM/PDE4D with 12-14 nM cAMP; >1 μM/all other PDEs).
技术参数
Specifications
| Quality Level | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| color | white to beige |
| solubility | DMSO: 2 mg/mL, clear |
| storage temp. | 2-8°C |
| SMILES string | FC(F)(C1=NC2=C(C(N)=N1)N=NN2C[C@@H]3OCCN(C3)CC4=NC=CS4)F |
| InChI | 1S/C14H15F3N8OS/c15-14(16,17)13-20-11(18)10-12(21-13)25(23-22-10)6-8-5-24(2-3-26-8)7-9-19-1-4-27-9/h1,4,8H,2-3,5-7H2,(H2,18,20,21)/t8-/m1/s1 |
| InChI key | VNLPYEMGHGDRRZ-MRVPVSSYSA-N |
| 长度(mm) | |
| 宽度(mm) | |
| 高度(mm) | |
| 重量(kg) |
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