Anti-Phospho-Cdc6-S54 antibody produced in rabbit,100UL,SAB5701916-100UL,Sigma

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订货号 0BM1301
品牌型号 Sigma SAB5701916-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins. [provided by RefSeq, Jul 2008]


Immunogen

A phospho specific peptide corresponding to residues surrounding S54 of human Cdc6


Physical form

Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.


技术参数 Specifications
biological sourcerabbit
Quality Level100
antibody product typeprimary antibodies
clonemonoclonal
formliquid
species reactivitymouse, human
concentration0.33 mg/mL
technique(s)western blot: 1:500-1:2000
UniProt accession no.Q99741
shipped inwet ice
storage temp.−20°C
target post-translational modificationphosphorylation (pSer52)
Gene Informationhuman ... CDC6(990)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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