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Biochem/physiol Actions
ES24 is an Eeyarestatin 1 analog that blocks protein translocation in vitro and more effectively enhances Sec61-mediated Ca2+ leakage from Endoplasmic Reticulum (ER). Apparently ES24 keep Sec61 in open position allowing Ca2+ ions to move freely through the aqueous channel present. It causes cell-type-specific Ca2+-dependent cell death.
blocks protein translocation in vitro and effectively enhances Sec61-mediated Ca2+ leakage from Endoplasmic Reticulum (ER).
| Quality Level | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| color | faint yellow to dark orange |
| solubility | DMSO: 2 mg/mL, clear |
| storage temp. | −20°C |
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¥ 1596.77
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¥ 1259.40
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¥ 9207.92
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¥ 5887.85
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¥ 238.17
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¥ 20380.83
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¥ 2617.87
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¥ 2173.94
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¥ 2888.88
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¥ 5990.26
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¥ 3662.39
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