Anti-TIMP2 Antibody, clone 8R5Q2, Rabbit Monoclonal,100UL,SAB5702264-100UL,Sigma

销售价: ¥ 3636.13 / 件
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订货号 0BL7522
品牌型号 Sigma SAB5702264-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix.


Immunogen

PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Recombinant protein of human TIMP2.


Application

WB


技术参数 Specifications
biological sourcerabbit
Quality Level100
conjugateunconjugated
materialcolorless
clone8R5Q2, monoclonal
formliquid
mol wt 22 kDa
species reactivityAfrican green monkey, rat, mouse, human
concentration1.00 mg/mL
technique(s)western blot: 1:500 - 1:1000
color colorless
isotypeIgG
immunogen sequenceVSLDVGGKKEYLIAGKAEGDGKMHITLCDFIVPWDTLSTTQKKSLNHRYQMGCECKITRCPMIPCYISSPDECLWMDWVTEKNINGHQAKFFACIKRSDGS
UniProt accession no.P16035
shipped inwet ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... TIMP2(7077)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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