Anti-Epstein-Barr BGLF4 Kinase (N-term) antibody produced in rabbit,100UG,SAB1300446-100UG,Sigma

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订货号 0BL7266
品牌型号 Sigma SAB1300446-100UG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

Epstein-Barr BGLF4 plays many key roles by phosphorylating several proteins including the viral DNA processivity factor BMRF1, EBNA1 or EBNA2. It is required for efficient lytic DNA replication and release of nucleocapsids from the nucleus. This protein contributes to the compaction of host cell chromatin in cells undergoing lytic replication, presumably by phosphorylating the host condensin complex and host TOP2A. BGLF4 induces disassembly of the nuclear lamina by phosphorylating with host LMNA, and phosphorylates substrates involved in capsid assembly and DNA packaging. It facilitates the switch from latent to lytic DNA replication by down-regulating EBNA1 replication function. This protein phosphorylates the viral immediate-early protein BZLF1.


Immunogen

BGL (1-30)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of Epstein-Barr BGLF4 Kinase.


Physical form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.


Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


技术参数 Specifications
biological sourcerabbit
Quality Level200
conjugateunconjugated
antibody formIgG fraction of antiserum
antibody product typeprimary antibodies
clonepolyclonal
formbuffered aqueous solution
species reactivityEpstein-Barr virus
technique(s)indirect ELISA: 1:1000
NCBI accession no.YP_401688
UniProt accession no.P13288
shipped indry ice
storage temp.−20°C
target post-translational modificationunmodified
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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