Anti-CD38 Antibody, clone 1G3, Rabbit Monoclonal,100UL,SAB5703045-100UL,Sigma

销售价: ¥ 3636.13 / 件
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订货号 0BL5647
品牌型号 Sigma SAB5703045-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

The protein encoded by this gene is a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5′-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Crystal structure analysis demonstrates that the functional molecule is a dimer, with the central portion containing the catalytic site. It is used as a prognostic marker for patients with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants.


Immunogen

PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Recombinant protein of human CD38.


Application

FC


技术参数 Specifications
biological sourcerabbit
Quality Level100
conjugateunconjugated
materialcolorless
clone1G3, monoclonal
formliquid
species reactivityhuman
concentration1 mg/mL
technique(s)flow cytometry: 1:50 - 1:200
color colorless
isotypeIgG
UniProt accession no.P28907
shipped inwet ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... CD38(952)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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