- 商品介绍
- 规格参数
- 包装参数
Biochem/physiol Actions
CSK is a cytoplasmic tyrosine kinase that has been shown to downregulate the tyrosine kinase activity of the c-src through tyrosine phosphorylation of the c-src carboxy terminus. A yeast 2-hybrid system has been used to identify proteins associated with CSK. The Src homology-3 (SH3) domain of CSK associates with a proline-rich region of PEP, a protein-tyrosine phosphatase expressed in hemopoietic cells. This association is highly specific and it is speculated that PEP may be an effector and/or regulator of CSK in T cells and other hemopoietic cells.
Physical form
Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.2 5mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.
Legal Information
PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany
| recombinant | expressed in baculovirus infected Sf9 cells |
| Quality Level | 200 |
| product line | PRECISIO® Kinase |
| assay | ≥70% (SDS-PAGE) |
| form | buffered aqueous glycerol solution |
| specific activity | 361-489 nmol/min·mg |
| mol wt | ~78 kDa |
| UniProt accession no. | P41240 |
| shipped in | dry ice |
| storage temp. | −70°C |
| Gene Information | human ... CSK(1445) |
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¥ 2013.69
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¥ 1302.89
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¥ 1451.54
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¥ 2068.25
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¥ 4173.75
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¥ 1956.41
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¥ 3812.28
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