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General description
GRK1 (rhodopsin kinase) is an enzyme that belongs to serine/threonine protein kinase family and expresses mainly in rod and cone photoreceptors. It has a crucial role in phosphorylation of photoactivated rhodopsin and hence starting steps in its deactivation. Monoclonal anti-rhodopsin kinase 1a antibody can be used in immunoprecipitation. Mouse anti-rhodopsin kinase 1a antibody reacts specifically with an epitope present in the C-terminal region of mouse, bovine, rat, chicken and human GRK1a. The product has shown no cross-reactivity with other G protein coupled kinases together with GRK1b.
Rhodopsin Kinase 1A encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates rhodopsin and initiates its deactivation.
Immunogen
derived from human GRK1
Application
Monoclonal anti-rhodopsin kinase 1a antibody can be used in indirect immunofluorescence and western blotting.
Physical form
Supplied in phosphate buffered saline containing 0.05% sodium azide.
| biological source | mouse |
| Quality Level | 200 |
| conjugate | unconjugated |
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone | G8, monoclonal |
| form | buffered aqueous solution |
| species reactivity | rat, bovine, chicken, human, mouse |
| technique(s) | immunoprecipitation (IP): suitable,indirect immunofluorescence: suitable,western blot: suitable |
| UniProt accession no. | Q15835 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human ... GRK1(6011) mouse ... Grk1(24013) rat ... Grk1(81760) |
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¥ 1148.92
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¥ 2068.25
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¥ 4039.86
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¥ 1956.41
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¥ 1653.62
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¥ 15214.65
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¥ 4404.38
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¥ 3852.13
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¥ 1783.21
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¥ 2869.87
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