- 商品介绍
- 规格参数
- 包装参数
Biochem/physiol Actions
Orraly active inhibitor of CCR2 and CCR5 receptors; Antiretroviral entry inhibitor.
Cenicriviroc is an orally available inhibitor of C-C chemokine CCR2 (IC50 = 5.9 nM) and CCR5 (IC50 = 0.29 nM) receptors, an antiretroviral entry inhibitor with anti-inflammatory activity. CCR5 chemokine receptor antagonists are believed to inhibit HIV entry by blocking interaction of viral coat protein gp120 with the receptor. CCR2 is involved with inflammatory-related disease states.
Disclaimer
Hygroscopic
| Quality Level | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| storage condition | desiccated |
| color | , faint green to green brown |
| solubility | DMSO: 2 mg/mL, clear |
| storage temp. | -10 to -25°C |
| SMILES string | OS(=O)(C)=O.CCCCOCCOC(C=C1)=CC=C1C2=CC=C3C(/C=C(C(NC4=CC=C([S@@+]([O-])CC5=CN=CN5CCC)C=C4)=O)\CCCN3CC(C)C)=C2 |
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¥ 1563.36
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¥ 1573.49
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¥ 9207.92
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¥ 3442.25
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¥ 3152.47
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¥ 10277.12
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